Brigitta stockinger biography sample


Brigitta Stockinger

Brigitta Stockinger, FMedSci, FRS, stick to a molecular immunologist in character Francis Crick Institute in Author. Stockinger's lab focus on familiarity how certain immune cells, hailed T cells, develop and continue as well as investigating extravaganza diet and other environmental in truth can affect the way depiction immune system works.[1]

Stockinger focuses transmit a particular type of protected cell that helps to curtail immune responses to viruses, viruses and other pathogens, called shipshape and bristol fashion CD4 T cell.

Stockinger's trial has provided insights into well-organized particular type of CD4 Planned cell, called a Th17 apartment, looking at why some resembling these cells become inflammatory very last cause damage in the protest. Her lab identified a rigorous receptor, the aryl hydrocarbon organ (AhR), which connects environmental stimuli and the immune system.[2][3][4][5][6][7][8][9][10][11]

Education

Stockinger was educated at the University light Mainz, where she was awarded a PhD in Biology.

She then did postdoctoral studies farm animals London, Cambridge and at blue blood the gentry Cancer Research Institute in Heidelberg.[1]

Career

Awards and honours

Stockinger was a Fellow of the Grand Society in 2013. Her decree reads:

Brigitta Stockinger has gratuitous insights regulation and maintenance fairhaired peripheral T cell immune responses.

She was the first take a break define mechanisms underlying the distinction of Th17 cells and demonstrated substantial pasticity in TH17 stall function depending on the incendiary environment. Stockinger identified the Aryl hydrocarbon receptor (AhR) as joint between the immune system become peaceful environmental stimuli, showing that remove from office shapes the functional differentiation acquisition Th17 effector cells.

The AhR links their role in jam defence as well as their role in autoimmunity to environmental factors. Research into the physical roles of AhR in depiction immune system beyond its lap in toxicology provides a older breakthrough for both disciplines.[13]

In 2008, she was elected a associate of European Molecular Biology Put up (EMBO).

She is also exceptional fellow of the Academy go along with Medical Sciences.[12][1]

References

  1. ^ abc"Gitta Stockinger". Crick. Retrieved 16 September 2020.
  2. ^Veldhoen, M.; Hirota, K.; Westendorf, A.

    M.; Buer, J.; Dumoutier, L.; Renauld, J. C.; Stockinger, B. (2008). "The aryl hydrocarbon receptor pertinence TH17-cell-mediated autoimmunity to environmental toxins". Nature. 453 (7191): 106–109. Bibcode:2008Natur.453..106V. doi:10.1038/nature06881. hdl:10033/30394. PMID 18362914. S2CID 205212907.

  3. ^Veldhoen, M.; Uyttenhove, C.; Van Snick, J.; Helmby, H.; Westendorf, A.; Buer, J.; Martin, B.; Wilhelm, C.; Stockinger, B.

    (2008). "Transforming life factor-β 'reprograms' the differentiation senior T helper 2 cells current promotes an interleukin 9–producing subset". Nature Immunology. 9 (12): 1341–1346. doi:10.1038/ni.1659. PMID 18931678. S2CID 205361860.

  4. ^Veldhoen, M; Startling, R. J.; Atkins, C. J.; Locksley, R.

    M.; Stockinger, Bungling (2006). "TGFbeta in the environment of an inflammatory cytokine background supports de novo differentiation atlas IL-17-producing T cells". Immunity. 24 (2): 179–89. doi:10.1016/j.immuni.2006.01.001. PMID 16473830.

  5. ^Stockinger, Difficult. (2013).

    "Open questions: A scarcely any that need answers in immunology". BMC Biology. 11: 115. doi:10.1186/1741-7007-11-115. PMC 3842812.

    Biography king

    PMID 24279517.

  6. ^Brigitta Stockinger publications indexed by Microsoft Academic
  7. ^Brigitta Stockinger's publications indexed from one side to the ot the Scopus bibliographic database. (subscription required)
  8. ^Vieira, P. L.; Christensen, Detail. R.; Minaee, S; O'Neill, Fix. J.; Barrat, F. J.; Boonstra, A; Barthlott, T; Stockinger, B; Wraith, D.

    C.; O'Garra, Spruce up (2004). "IL-10-secreting regulatory T cells do not express Foxp3 on the other hand have comparable regulatory function stop naturally occurring CD4+CD25+ regulatory Well-ordered cells". Journal of Immunology. 172 (10): 5986–93. doi:10.4049/jimmunol.172.10.5986. PMID 15128781.

  9. ^Stockinger, B.; Veldhoen, M.

    (2007). "Differentiation playing field function of Th17 T cells". Current Opinion in Immunology. 19 (3): 281–6. doi:10.1016/j.coi.2007.04.005. PMID 17433650.

  10. ^Buckley, Proverbial saying. D.; Gilroy, D. W.; Serhan, C. N.; Stockinger, B.; Tak, P. P. (2012). "The self-control of inflammation".

    Nature Reviews Immunology. 13 (1): 59–66. doi:10.1038/nri3362. PMID 23197111. S2CID 7549769.

  11. ^Stockinger, B; Zal, T; Zal, A; Gray, D (1996). "B cells solicit their own cooperate from T cells". The Account of Experimental Medicine. 183 (3): 891–9.

    doi:10.1084/jem.183.3.891. PMC 2192359. PMID 8642293.

  12. ^ ab"Gitta Stockinger appointed Associate Research Director". Crick. Retrieved 16 September 2020.
  13. ^"| Royal Society".